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The liver stores B12, and these stores can last a significant time (up to several years for non-deficient individuals), but when they are depleted, it takes consistent input to rebuild and maintain them

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3.5 Clostridium in primary Sjgrens syndrome The primary Sjgrens syndrome (pSS) is a type of AD characterized by inflammation and destruction of exocrine glands, primarily manifesting as xerophthalmia and xerostomia (201)